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Recombinant Anti-Troponin I Mab (CAT#: HOM-19489)

Datasheet
DESCRIPTION CATALOG # SIZE PRICE
Recombinant Human Anti-Human Troponin I Monoclonal Antibody HOM-19489 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant humanized antibody expressed in CHO binding to human Troponin I.
  • Target
  • TNNI3
  • Type
  • Human IgG
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • ELISA, WB, IHC, FCM, IP, IF. Optimal dilutions/concentrations should be determined by the end user.
  • Clone
  • Monoclonal
  • Molecular Weight
  • 145.41 kDa
  • Purity
  • >95.0% as determined by analysis by RP-HPLC & analysis by SDS-PAGE.
  • Storage
  • Store it under sterile conditions at -20 °C upon receiving. Recommend to pack the antibody into smaller quantities for optimal storage.
  • Stability
  • Samples are stable for up to twelve months from date of receipt at - 20°C and are stable for six months at 4 °C.
  • Ship
  • 2-8°C, BLUE ICE

BACKGROUND

  • Antigen Description
  • Troponin I is a part of the troponin complex. It binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it, myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle. The letter I is given due to its inhibitory character.
  • Function
  • actin binding; calcium channel inhibitor activity; calcium-dependent protein binding; protein binding; protein domain specific binding; protein kinase binding; troponin C binding; troponin T binding;
  • Synonyms
  • TNNI3; troponin I type 3 (cardiac); troponin I, cardiac; troponin I, cardiac muscle; CMH7; TNNC1; RCM1; cTnI; CMD2A; CMD1FF; MGC116817;

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